Request for Information (RFI): Inviting Comments and Suggestions on a Framework for the NIH-Wide Strategic Plan for Fiscal Years 2027-2031

"The purpose of the NIH-Wide Strategic Plan is to communicate how NIH will advance its mission to support research in pursuit of fundamental knowledge about the nature and behavior of living systems, and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability.

"The current NIH-Wide Strategic Plan, covering FY21-FY25, was submitted to Congress in July 2021. As part of implementing the 21st Century Cures Act (P.L. 114-255), NIH will update its Strategic Plan, no less than once every six years. The agency is currently developing the NIH-Wide Strategic Plan for FY27-FY31 and anticipates releasing it early FY27.

"The NIH-Wide Strategic Plan highlights NIH’s approach towards the achievement of its mission while ensuring good stewardship of taxpayer funds. It is not intended to outline the myriad of important research opportunities for specific diseases or conditions. Nor will it focus on the specific research missions of each component Institute, Center and Office.

"This RFI invites input from stakeholders throughout the scientific research, advocacy, and clinical practice communities, as well as the general public, regarding the above proposed framework for the NIH-Wide Strategic Plan for FY27-FY31. The NIH seeks comments on, but not limited to, NIH’s Goals across the three Priorities articulated in the framework—including potential benefits, drawbacks, opportunities, or challenges, and other areas of focus for consideration."

Responses must be received by 11:59:59 pm (ET) on May 16, 2026.

Read the full notice online